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蛋白质/抗原/多肽 >> 重组蛋白
重组CD300LB蛋白
重组CD300LB蛋白图片
交货期: 1周
索取资料及报价
交货期:1周
产品别名:Recombinant CD300LB
Recombinant CD300 molecule like family member b protein
产品介绍
基因名:

CD300LB


产品别名:

CD300b; CLM-7; CLM7; CMRF35-A2; IREM-3; IREM3; TREM-5; TREM5; CD300LB; CD300 molecule like family member b; CD300 molecule like family member b; CMRF35-like molecule 7; CD300 antigen like family member B; immune receptor expressed on myeloid cells 3; leukocyte mono-Ig-like receptor 5; triggering receptor expressed on myeloid cells 5;


背景信息:
CD300LB, also known as CD300b, LMIR5, CLM-7, and IREM?3, is a glycoprotein member of the immunoglobulin superfamily. LMIR5 is expressed on the surface of myeloid lineage cells. It forms noncovalent cis?homodimers and cis-heterodimers with other CD300 family proteins, and the composition of these dimers affects the cellular response. Antibody cross?linking of LMIR5 induces mast cell granule release and cytokine production as well as its tyrosine phosphorylation of LMIR5 (in human). LMIR5 interacts with TIM1 and TIM4 which regulate T cell activation and are themselves binding partners. TIM1 interactions with LMIR5 mediate mast cell activation and the accumulation of neutrophils at sites of TIM1 up?regulation on damaged renal tubule epithelial cells. Acts as an activating immune receptor through its interaction with ITAM-bearing adapter TYROBP, and also independently by recruitment of GRB2.

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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