蛋白质/抗原/多肽 >> 重组蛋白
重组叉头蛋白R2
产品介绍 基因名: FOXR2 产品别名: FOXN6; FOXR2; forkhead box R2; forkhead box R2; forkhead box protein R2; forkhead box protein N6; 叉头蛋白R2; 背景信息: The Forkhead-box (FOX) genes comprise a superfamily of at least 43 members that express proteins which are involved in transcriptional regulation and may be associated with the pathogenesis of various cancers. FOXR2 (Forkhead box protein R2), also known as FOXN6 (Forkhead box protein N6), is a 311 amino acid nuclear protein that belongs to the FOX family and contains one fork-head DNA-binding domain. Like other members of the FOX family, FOXR2 is not abundantly expressed in normal tissues but is found at very high levels in breast cancer and primary cancer cell lines and is thought to act as a transcription factor. Through chromosomal aberrations such as retroviral integration, gene amplification or translocation, FOXR2 may be involved the development of certain invasive carcinomas. 标签:His-tag |
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