蛋白质/抗原/多肽 >> 重组蛋白
重组10号染色体开放阅读框30蛋白
产品介绍 基因名: Bend7 产品别名: 1110017O21Rik; E130319B15Rik; Bend7; BEN domain containing 7; BEN domain containing 7; BEN domain-containing protein 7; 10号染色体开放阅读框30; 背景信息: BEND7 is a 519 amino acid protein that contains a BEN domain. BEN domain mediates protein–DNA and protein–protein interactions during chromatin organization and transcription. BEN domain may play a role in organization of viral DNA during replication or transcription. BEND7 exists as three independently spiced isoforms and the gene that encodes BEND7 maps to chromosome 10p13. Chromosome 10 contains over 800 genes and 135 million nucleotides, making up nearly 4.5% of the human genome. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome. The chromosome 10 encoded gene ERCC6 is important for DNA repair and is linked to Cockayne syndrome which is characterized by extreme photosensitivity and premature aging. Tetrahydrobiopterin deficiency and a number of syndromes involving defective skull and facial bone fusion are also linked to chromosome 10. 标签:His-tag |
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