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蛋白质/抗原/多肽 >> 重组蛋白
重组睾丸核蛋白NUT
重组睾丸核蛋白NUT图片
交货期: 1周
索取资料及报价
交货期:1周
产品别名:Recombinant Nutm1
Recombinant NUT midline carcinoma, family member 1 protein
产品介绍
基因名:

Nutm1


产品别名:

4932438M10; Nut; Nutm1; NUT midline carcinoma, family member 1; NUT midline carcinoma, family member 1; NUT family member 1; nuclear protein in testis (Nut); protein NUT; 睾丸核蛋白NUT;


背景信息:
nuclear protein in testis is a 1,132 amino acid protein that is specifically expressed in testis. Belonging to the FAM22 family, NUT shuttles between nucleus and cytoplasm via a leptomycin-sensitive pathway. It is suggested that the translocation of the NUT gene is the cause of nuclear protein in testis midline carcinomas (NMC). NMCs are highly aggressive carcinomas typically arising in midline structures in young individuals. These carcinomas are characterized by the presence of a chromosomal rearrangement of the NUT gene on chromosome 15 (15q14), which results in a chromosomal translocation most commonly involving the BRD4 gene on chromosome 19p13. Endogenous BRD-NUT fusion proteins contribute to carcinogenesis by associating with chromatin and interfering with epithelial differentiation.

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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