蛋白质/抗原/多肽 >> 重组蛋白
重组NAALADL2蛋白
产品介绍 基因名: NAALADL2 产品别名: NAALADL2; N-acetylated alpha-linked acidic dipeptidase like 2; N-acetylated alpha-linked acidic dipeptidase like 2; inactive N-acetylated-alpha-linked acidic dipeptidase-like protein 2; N-acetylated alpha-linked acidic dipeptidase 2; NAALADase L2; glutamate carboxypeptidase II-type non-peptidase homologue; NAALADL2蛋白; 背景信息: NAALADL2 is a 795 amino acid single-pass type II membrane protein that belongs to the peptidase M28 family and M28B subfamily. Existing as two alternatively spliced isoforms, NAALADL2 is expressed at highest levels in placenta and kidney, and has also been observed in certain embryonic tissues. NAALADL2 may be catalytically inactive. The gene encoding NAALADL2 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3. 标签:His-tag |
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