蛋白质/抗原/多肽 >> 重组蛋白
重组巨噬细胞炎性蛋白3样蛋白1
产品介绍 基因名: CCL3L3 产品别名: 464.2; D17S1718; G0S19-2; LD78; LD78BETA; SCYA3L; SCYA3L1; CCL3L3; C-C motif chemokine ligand 3 like 3; C-C motif chemokine ligand 3 like 3; C-C motif chemokine 3-like 1; G0/G1 switch regulatory protein 19-2; LD78-beta(1-70); chemokine (C-C motif) ligand 3-like 3; chemokine (C-C motif) ligand 3-like, centromeric; small inducible cytokine A3-like 1; tonsillar lymphocyte LD78 beta protein; 巨噬细胞炎性蛋白3样蛋白1; 背景信息: C-C Motif Chemokine 3-Like 1 (CCL3L1) is a secreted protein that belongs to the intercrine beta (chemokine CC) family. CCL3L1 is a ligand for CCR1, CCR3 and CCR5. CCL3L1 binds to several chemokine receptors including chemokine binding protein 2 and chemokine (C-C motif) receptor 5 (CCR5). CCR5 is a co-receptor for HIV, and binding of this protein to CCR5 inhibits HIV entry. The processed form LD78-beta (3-70) shows a 20-fold to 30-fold higher chemotactic activity and is a very potent inhibitor of HIV-1-infection. The copy number of this gene varies among individuals: most individuals have 1-6 copies in the diploid genome, although rare individuals have zero or more than six copies. The human genome reference assembly contains two full copies of the gene (CCL3L3 and CCL3L1) and a partial pseudogene. This record represents the more centromeric full-length gene. 标签:His-tag |
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