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EGTA, AM

品牌
J&K
CAS
99590-86-0
货号
137958
规格纯度
90%, 是 EGTA 的膜渗透形式,可以被动地载入到细胞中产生细胞内的 EGTA, EGTA-AM 同时为 Ca2+ 螯合剂
参考价格
2690 *本价格含增值税费
促销
服务
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数量
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产品名称:
99590-86-0
EGTA, AM
产品介绍:

基本信息

分子式C26H40N2O18
分子量668.60
MDL编码MFCD00077339
存储条件Freezer -20℃

产品描述

EGTA-​AM is a membrane permeable form of EGTA, can be passively loaded into cells to generate intracellular EGTA; EGTA-​AM is also a Ca2+ chelator with slow chelating dynamics.

体外研究

EGTA-AM (50 μM) markedly reduces the asynchronous excitatory postsynaptic currents (aEPSC) to 58.9 ± 8.1% of the control level, but only reduces the synchronous excitatory postsynaptic currents (EPSCs), measured as charge transfer produced by the stimulation train[1].

参考文献

[1]. Li MJ, et al. Cholinergic and glutamatergic transmission at synapses between pedunculopotine tegmental nucleus axonal terminals and A7 catecholamine cell group noradrenergic neurons in the rat. Neuropharmacology. 2016 Nov;110(Pt A):237-50

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