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5,6-Dihydrouridine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
5,6-Dihydrouridine图片
CAS NO:5627-05-4
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
5mg电议

产品介绍
5,6-Dihydrouridine是在细菌,真核生物和一些古细菌中的tRNA的D-环中的保守位置中发现的修饰碱基。
Cas No.5627-05-4
别名5,6-二氢尿苷
Canonical SMILESOC[C@@H]1[C@H]([C@H]([C@H](N2CNC(NC2=O)=O)O1)O)O
分子式C8H13N3O6
分子量247.21
溶解度DMSO : ≥ 125 mg/mL (505.64 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

5,6-Dihydrouridine is a modified base found in conserved positions in the D-loop of tRNA in Bacteria, Eukaryota, and some Archaea.

5,6-Dihydrouridine (Dihydrouridine) is one of the posttranscriptionally modified nucleosides. It is a product of the reduction of uridine (U), and can be further modified to 5-methyldihydrouridine (m5D). 5,6-Dihydrouridine is commonly present in the tRNA from Bacteria, Eukaryota, and some Archaea. It is identified in six positions in the "D-loop" of the tRNA (16, 17, 20a, 20b) and in position 47 in the variable loop[1].

[1]. Kasprzak JM, et al. Molecular evolution of dihydrouridine synthases. BMC Bioinformatics. 2012 Jun 28;13:153.