ABI-274 is a novel, orally bioavailable, highly potent and selective tubulin/mitotic inhibitor (specifically a microtubule destabilizer) targeting the colchicine binding site, belonging to the so called colchicine binding site inhibitor (CBSI). It has shown potent anticancer activities in vitro and in vivo, as well as favorable pharkacokinetics such as good oral bioavailability.
纯度:≥98%
CAS:1253697-93-6