Tyrothricin 是一种从短芽孢杆菌中分离出来的多肽抗生素混合物,由酪氨酸和短杆菌肽组成。
Cas No. | 1404-88-2 |
别名 | 酪丝菌素 |
分子式 | C66H87N13O13(for Tyrocidine A) |
分子量 | 1270.5 |
溶解度 | DMF: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Tyrothricin is a polypeptide antibiotic mixture produced by B. brevis. Tyrothricin is a mixture of tyrocidine and gramicidin that has rapid in vitro bactericidal activity against T. microdentium, T. macrodentium, T. vincentii, T. buccalis, T. mucosum, T. vaginalis, T. cruzi, and L. tropica. Preclinical studies demonstrate that intravenous use of tyrothricin leads to hemolysis-induced lethality (LD50s = 0.4 and 0.3 mg/kg, in dogs and mice, respectively) and damages liver, kidney, and olfactory tissues. Formulations containing tyrothricin are used topically to treat bacterial skin infections. |