CAS NO: | 1615713-87-5 |
包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
Cas No. | 1615713-87-5 |
化学名 | 1-[[6-(dimethylamino)-5-methyl-4-pyrimidinyl]methyl]-N-(2-hydroxyethyl)-6-methyl-1H-pyrrolo[3,2-b]pyridine-3-carboxamide |
Canonical SMILES | CC1=CN=C2C(N(CC3=C(C)C(N(C)C)=NC=N3)C=C2C(NCCO)=O)=C1 |
分子式 | C19H24N6O2 |
分子量 | 368.4 |
溶解度 | DMF: 2mg/mL,DMSO: 2mg/mL,DMSO:PBS (pH 7.2) (1:4): 0.2mg/mL |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | DprE1-IN-2 (compound 18) is a potent DprE1 inhibitor with an IC50 of 28 nM. DprE1-IN-2 has antituberculosis effect[1]. DprE1-IN-2 (compound 18; oral; 100 mg/kg) has t1/2 of 0.9 hours and Cmax of 70 μM in BALB/c Mice[1]. References: |