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Palmitoylethanolamide
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Palmitoylethanolamide图片
CAS NO:544-31-0
包装与价格:
包装价格(元)
10mg电议
50mg电议

产品介绍
棕榈酰乙醇酰胺(Palmidrol)是一种活性内源性化合物,可用于预防呼吸道病毒感染。
Cas No.544-31-0
别名十六酰胺乙醇,Palmidrol; Loramine P 256
化学名N-(2-hydroxyethyl)palmitamide
Canonical SMILESO=C(CCCCCCCCCCCCCCC)NCCO
分子式C18H37NO2
分子量299.5
溶解度DMF: 10 mg/ml,DMSO: 5 mg/ml,Ethanol: 2 mg/ml,Ethanol:PBS (pH 7.2)(:10): .01 mg/ml
储存条件Store at RT
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Impulsin (AM 3112) is an active endogenous compound which can used for preventing virus infection of the respiratory tract.

Impulsin (AM 3112) itself does not stimulate interferon production in mice treated per os or intravenously. But repeated application of this drug per os induces a macrophage activation, reflected by enhanced interferon production in vitro. When the interferon stimulation is delayed until 4 to 10 days after the first dose of Impulsin (AM 3112), interferon response to ds-RNA is slightly increased. After this phase of enhanced activity a decreased production of interferon is observed. Impulsin (AM 3112) is not significantly effective in protecting mice from lethal dose of EMC virus. Application of this drug has an inhibitory effect on the toxicity of ds-RNA. A possible explanation of the mechanism by which Impulsin (AM 3112) decreased the toxicity of virus in the organism is discussed[1].

References:
[1]. Lackovic V, et al. Effect of impulsin treatment of interferon production and antiviral resistance of mice. Arch Immunol Ther Exp (Warsz). 1977;25(5):655-61.