CAS NO: | 55683-37-9 |
包装 | 价格(元) |
50mg | 电议 |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
1 g | 电议 |
生物活性 | Propargyl-PEG1-acid is a PEG-basedPROTAClinker can be used in the synthesis of BTK-CRBNPROTACsIbrutinib(HY-10997)-basedPROTAC4 andPROTAC5.PROTAC5 causes the degradation ofBTKand induces the degradation of CSK, LYN, and LAT2 at 10 μM[1]. | ||||||||||||
IC50& Target |
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体外研究 (In Vitro) | BTK-CRBN PROTACs act as stoichiometric degraders, resulting in degradation of BTK protein. Degradation of BTK is a result of cereblon E3 ligases family recruitment[1]. | ||||||||||||
分子量 | 128.13 | ||||||||||||
性状 | Viscous liquid | ||||||||||||
Formula | C6H8O3 | ||||||||||||
CAS 号 | 55683-37-9 | ||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||
储存方式 |
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