19,20-Epoxycytochalasin C 是一种细胞松弛素,是一种来自 Nemania sp. 的真菌代谢物。
Cas No. | 189351-79-9 |
别名 | 19,20-环氧细胞松弛素C |
Canonical SMILES | O=C1[C@@](O)(C)[C@H](O2)[C@@H]2[C@@H](OC(C)=O)[C@@]34[C@@]([C@H](CC5=CC=CC=C5)NC4=O)([H])C(C)=C(C)[C@@H](O)[C@]3([H])/C=C/C[C@@H]1C |
分子式 | C30H37NO7 |
分子量 | 523.6 |
溶解度 | DMF: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | 19,20-Epoxycytochalasin C is a fungal metabolite originally isolated from Nemania sp. UM10M. It inhibits the growth of chloroquine-sensitive and -resistant strains of P. falciparum (IC50s = 0.07 and 0.05 ng/ml, respectively) without inducing cytotoxicity in Vero cells (IC50 = >4,760 ng/ml). 19,20-Epoxycytochalasin C is also phytotoxic, reducing growth of lettuce and bentgrass plants when used at a concentration of 1 mg/ml. |