您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > Platencin
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Platencin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Platencin图片
CAS NO:869898-86-2
包装与价格:
包装价格(元)
100μg电议
500μg电议

产品介绍
Platencin 是一种天然的广谱革兰氏阳性抗生素,从 S.
Cas No.869898-86-2
别名平板素
Canonical SMILESO=C1C=C[C@@](CC([C@]2([H])C3)=C)(CC2)[C@]3([H])[C@]1(C)CCC(NC4=C(O)C(C(O)=O)=CC=C4O)=O
分子式C24H27NO6
分子量425.5
溶解度DMF: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Platencin is a natural, broad spectrum Gram-positive antibiotic isolated from S. platensis, which is also the source of platensimycin . Platencin inhibits two key enzymes in bacterial fatty acid synthesis, β-ketoacyl-ACP synthases II and III (FabF and FabH, respectively), unlike platensimycin which only targets FabF. The IC50 values for platencin against FabF and FabH are 1.95 and 3.91 μg/ml, respectively. It does not exhibit cross-resistance to antibiotic resistant bacterial strains, including methicillin-resistant S. aureus, vancomycin-intermediate S. aureus, and vancomycin-resistant Enterococci. For these reasons, platencin has potential applications in fighting antibiotic resistant bacteria.