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PNU-248686A
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
PNU-248686A图片
CAS NO:341498-89-3
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
20mg电议

产品介绍
PNU-248686A是一种新型的基质金属蛋白酶(MMP)抑制剂。
Cas No.341498-89-3
Canonical SMILESO=C(O)[C@](CSC1=CC=CC=C1)(O)CS(=O)(C2=CC=C(C3=CC=C(Cl)C=C3)C=C2)=O.[Na]
分子式C22H19ClNaO5S2
分子量485.96
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

PNU-248686A is a novel matrix metalloproteinase (MMP) inhibitor.

PNU-248686A is an orally active matrix metalloproteinase (MMP) inhibitor developed for the treatment of solid tumors over-expressing MMPs[1].

[1]. Frigerio E, et al. Determination of PNU-248686A, a novel matrix metalloproteinase inhibitor, in human plasma by liquid chromatography-tandem mass spectrometry, following protein precipitation in the 96-well plate format. J Chromatogr A. 2003 Feb 14;987(1-2):249-56.