您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > PROTAC IRAK4 degrader-3
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
PROTAC IRAK4 degrader-3
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
PROTAC IRAK4 degrader-3图片
CAS NO:2374122-43-5
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品介绍
PROTAC IRAK4 degrader-3 是一种基于von Hippel-LindauIRAK4降解剂 PROTAC。
生物活性

PROTACIRAK4 degrader-3 is a PROTAC-inducedIRAK4degrader based onvon Hippel-Lindau[1].

IC50& Target[1]

IRAK4

 

体外研究
(In Vitro)

PROTAC IRAK4 degrader-3 (0.01~10 μM; 2 hours; PBMCs) mediated degradation is occurring in a proteasome dependent manner[1].
PROTAC IRAK4 degrader-3 (0.01~100 μM; 18 hours; PBMCs) is capable of completely blocking IL-6 secretion[1].

Western Blot Analysis[1]

Cell Line:PBMCs
Concentration:0.01~10 μM
Incubation Time:2 hours
Result:IRAK4 PROTAC-mediated degradation was occurring in a proteasome dependent manner.
分子量

1086.28

Formula

C57H68FN11O8S

CAS 号

2374122-43-5

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.