FGFR-IN-3 (compound 6) is an orally active, potent and BBB-penetratedFGFR(fibroblast growth factor receptor) modulator. FGFR-IN-3 shows neuroprotective activity. FGFR-IN-3 can be used for neurodegenerative diseases research^[1].

FGFR-IN-3 (compound 6) is sufficiently lipophilic (logP = 2.2) to passively permeate across the blood-brain barrier, and further increase in molecular lipophilicity results in boosting MBI (mechanism-based inactivation) activity^[1].

383.44

C₁₈H₂₇F₂N₅O₂

2488762-63-4

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.