CAS NO: | 5812-07-7 |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
50mg | 电议 |
100mg | 电议 |
200mg | 电议 |
500mg | 电议 |
生物活性 | SU4312 is the racemate of (Z)-SU4312 and (E)-SU4312. (Z)-SU4312 inhibitsPDGFRand FLK-1 withIC50s of 19.4 and 0.8 μM, respectively. (E)-SU4312 inhibitsPDGFR, FLK-1,EGFR, HER-2, andIGF-1RwithIC50s of 24.2, 5.2, 18.5, 16.9 and 10.0 μM, respectively[1]. | ||||||||||||||||
IC50& Target |
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体外研究 (In Vitro) | Receptor tyrosine kinases (RTKs) have been shown to be important mediators of cellular signal transduction in cells. Many RTKs have been shown to be oncogene products implicating their role in the transformation process associated with human cancers[1]. | ||||||||||||||||
分子量 | 264.32 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C17H16N2O | ||||||||||||||||
CAS 号 | 5812-07-7 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 |
*该产品在溶液状态不稳定,建议您现用现配,即刻使用。 | ||||||||||||||||
溶解性数据 | In Vitro: DMSO : 50 mg/mL(189.16 mM;Need ultrasonic) 配制储备液
* 请根据产品在不同溶剂中的溶解度,选择合适的溶剂配制储备液;该产品在溶液状态不稳定,建议您现用现配,即刻使用。 In Vivo: 请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照In Vitro方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用;
以下溶剂前显示的百
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