包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
生物活性 | Valproic acid-d14 (sodium) is deuterium labeled Valproic acid (sodium). Valproic acid sodium salt (Sodium Valproate) is anHDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibitsHDAC1(IC50, 400 μM), and induces proteasomal degradation ofHDAC2. Valproic acid sodium salt activates Notch1 signaling and inhibits proliferation in small cell lungcancer(SCLC) cells. Valproic acid sodium salt is used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches. |
体外研究 (In Vitro) | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
分子量 | 180.28 |
Formula | C8HD14NaO2 |
运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |