Valproic acid-d4 sodium

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包装与价格：

包装	价格(元)
1mg	电议
5mg	电议

产品名称

VPA-d4 sodium
2-Propylpentanoic Acid-d4 sodium

产品介绍

Valproic acid-d4 (VPA-d4) sodium 是 Valproic acid 的氘代物。Valproic acid (VPA; 2-Propylpentanoic Acid) 是一种HDAC抑制剂，IC₅₀值为 0.5-2 mM，抑制HDAC1的活性，(IC₅₀，400 μM)，同时可诱导HDAC2的降解。Valproic acid 激活Notch1<

生物活性	Valproic acid-d4 (VPA-d4) sodium is the deuterium labeled Valproic acid. Valproic acid (VPA; 2-Propylpentanoic Acid) is anHDACinhibitor, withIC₅₀in the range of 0.5 and 2 mM, also inhibitsHDAC1(IC₅₀, 400 μM), and induces proteasomal degradation ofHDAC2. Valproic acid activatesNotch1signaling and inhibits proliferation in small cell lungcancer(SCLC) cells. Valproic acid sodium salt is used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches.
体外研究 (In Vitro)	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].
分子量	170.22
Formula	C₈H₁₁D₄NaO₂
中文名称	丙戊酸 d4 (钠盐)
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.