CAS NO: | 2170830-26-7 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | TGFBR1-IN-1 is anALK5inhibitor extracted from patent WO2018004290A1, Compound 33, has anIC50of 10-100 nM[1]. | |
IC50& Target[1] |
| |
体外研究 (In Vitro) | Transforming Growth Factor-β (TGF-β) signaling regulates various cellular responses such as cell proliferation, differentiation, cell migration and cell death. TGF-β has at least three isoforms TGF-β1, TGF-β2 and TGF-β3. TGF-β1 is two well-conserved single membrane serine/threonine kinase type I (ALK5). ALK5 inhibitos can be used for treating fibrotic disease, tumor, inflammatory disease, and autoimmune disease[1]. | |
分子量 | 427.48 | |
Formula | C23H17N5O2S | |
CAS 号 | 2170830-26-7 | |
运输条件 | Room temperature in continental US; may vary elsewhere. | |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |