CAS NO: | 2442519-59-5 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | THRX-144644 is a Lung-restrictedALK5inhibitor with anIC50value of 0.14 nM. THRX-144644 avoids systemic toxicities associated with TGFβ pathway inhibition[1]. | ||||||||
IC50& Target[1] |
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体外研究 (In Vitro) | THRX-144644 (1-10000 nM; 1 h) inhibits ALK5 with an IC50value of 23 nM in human BEAS2B cell line. | ||||||||
体内研究 (In Vivo) | THRX-144644 (2-60 mg/kg; Inhalation: nebulizer, daily, for 14 days) is a Lung-selective inhibitor and targets to the lungs in Sprague Dawley rats[1].
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分子量 | 512.00 | ||||||||
Formula | C26H28ClF2N7 | ||||||||
CAS 号 | 2442519-59-5 | ||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |