CAS NO: | 188589-66-4 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | Cl-4AS-1, a potent steroidalandrogen receptor(AR)agonist (IC50= 12 nM), is also an inhibitor of 5α-reductase types I and II (IC50 = 6 and 10 nM, respectively)[1][2]. | ||||||||
IC50& Target | IC50: 12 nM (androgen receptor); 6 nM (5α-reductase types I); 10 nM (5α-reductase types II)[1][2] | ||||||||
体外研究 (In Vitro) | Cl-4AS-1 suppresses MMP-1 promoter activity in 22Rv1 human prostate cancer cells[1]. | ||||||||
体内研究 (In Vivo) | Cl-4AS-1 produces no significant reduction in prostate weight in intact animals and in castrates rats caused a significant increase of ventral prostate weight[1].
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分子量 | 441.01 | ||||||||
Formula | C26H33ClN2O2 | ||||||||
CAS 号 | 188589-66-4 | ||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |