Exemestane-D2 (FCE 24304-D2) is the deuterium labeled Exemestane. Exemestane (FCE 24304) is a selective, irreversible and orally active steroidalaromataseinhibitor withIC₅₀s of 30 nM and 40 nM forhuman placental andrat ovarianaromatase, respectively. Exemestane can be used for hormone-dependent breastcancerresearch^[1][2].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

298.42

C₂₀H₂₂D₂O₂

依西美坦 D2

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.