AC-186 是一种选择性的非甾体雌激素受体 β (ERβ) 激动剂，对 ERβ 和 ERα 的EC50分别为 6 nM 和 5000 nM。AC-186 在帕金森病大鼠模型中具有神经保护作用。
| 生物活性 | AC-186 is a selective non-steroidalestrogen receptorβ(ERβ) agonist withEC50s of 6 nM and 5000 nM forERβandERα, respectively. AC-186 shows gender specific neuroprotection in a Parkinson’s Disease rat model[1]. |
| IC50& Target[1] | ERβ 6 nM (EC50) | ERα 5000 nM (EC50) |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
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