LSD1/ER-IN-1

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LSD1/ER-IN-1

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

包装与价格：

包装	价格(元)
100mg	电议
250mg	电议
500mg	电议

产品介绍

LSD1/ER-IN-1 (compound 11g) 是一种有效的ER和LSD1抑制剂，其IC₅₀为 1.55 μM (LSD1)。LSD1/ER-IN-1 对ERα蛋白有高亲和力选择性，α/β 比为7.11。LSD1/ER-IN-1 对 MCF-7 乳腺癌细胞具有良好的抗增殖活性，其IC₅₀为8.79 μM。

生物活性

LSD1/ER-IN-1 (compound 11g) is a potentERandLSD1inhibitor, with anIC₅₀of 1.55 μM (LSD1). LSD1/ER-IN-1 has high affinity selectivity forERαprotein, with α/β ratio of 7.11. LSD1/ER-IN-1 shows good antiproliferative activity against MCF-7 breastcancercells, with anIC₅₀of 8.79 μM^[1].

IC₅₀& Target

ERα

ERβ

体外研究
(In Vitro)

LSD1/ER-IN-1 (compound 11g) (0-30 μM, 24 h) induces apoptosis in MCF-7 cells in a dose-dependent manner^[1].

分子量

455.46

Formula

C₂₃H₁₈FNO₆S

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.