Nomegestrol is a potent and orally available progestin, acts as a selective fullprogesterone receptoragonist, with aK_dof 5.44 nM for rat uterineprogesterone receptor, and has moderate antiandrogenic activity and strong antiestrogenic activity.

Kd: 5.44 nM (Rat uterine progesterone receptor)^[1]

Nomegestrol is a progestin, has high binding affinity at progesterone receptor, with a K_dof 5.44 nM for rat uterine progesterone receptor^[1]. Nomegestrol acetate (NOMAC) is a higly selective progesterone receptor full agonist, but shows no or little binding affinity at other steroid receptors, such as the androgen and glucocorticoid receptors. Nomegestrol acetate has moderate antiandrogenic activity and strong antiestrogenic activity^[2].

328.45

C₂₁H₂₈O₃

58691-88-6

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.