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Phytohemagglutinin P
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
包装与价格:
包装价格(元)
5mg电议
10mg电议
50mg电议
100mg电议
200mg电议
500mg电议

产品名称
PHA-P
产品介绍
Phytohemagglutinin P (PHA-P) 是一种有丝分裂原,可选择性刺激血源性或淋巴样单核细胞来源的细胞。
生物活性

Phytohemagglutinin P (PHA-P) is a mitogen known to selectively stimulate cells of hematogenous or lymphoid monocytic origin[1].

体外研究
(In Vitro)

Phytohemagglutinin-P (10 μg/ml; 24-48hous)-stimulated decidual CD8+T lymphocytes produces high levels of both interferon gamma and interleukin (IL) 8, and low levels of granulocyte-macrophage colony-stimulating factor (CSF2), IL1B, IL2, IL6, IL10, IL12, and tumor necrosis factor; these did not vary with gestational age[2].

体内研究
(In Vivo)

Phytohemagglutinin-P (25 and 50 mg/kg; i.p.; daily for 15 days; male Sprague-Dawley rats) shows a decrease in longitudinal bone growth, in the number of chondrocytes, in the thickness of cartilage plate, in the metaphyseal mass of hard tissue, in the percentage of calcified cartilage core, and in the number of osteoblasts per mm of bone surface. Additionally, PHA-P increases the number of osteoclasts, the number of labeled osteoclastic nuclei, and the average number of nuclei per osteoclast[1].

性状

Solid

结构分类
  • Others
来源
  • Plants
  • Leguminosae
  • Glycine max(L.) merr
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

溶解性数据
In Vitro: 

H2O : 10 mg/mL(Need ultrasonic and warming)

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照In Vitro方式配制澄清的储备液,再依次添加助溶剂:

——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比;如在配制过程中出现沉淀、析出现象,可以通过加热和/或超声的方式助溶

  • 1.

    请依序添加每种溶剂: PBS

    Solubility: 100 mg/mL (Infinity mM); Clear solution; Need ultrasonic and warming and heat to 60℃

*以上所有助溶剂都可在本网站选购。