| Cas No. | 673-49-4 |
| 别名 | N-Ω-乙酰基组胺,N-Omega-acetylhistamine |
| 化学名 | N-[2-(1H-imidazol-5-yl)ethyl]-acetamide |
| Canonical SMILES | O=C(C)NCCC1=CNC=N1 |
| 分子式 | C7H11N3O |
| 分子量 | 153.2 |
| 溶解度 | DMF: 10 mg/ml,DMSO: 5 mg/ml,Ethanol: 10 mg/ml,PBS (pH 7.2): 10 mg/ml |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | N-acetyl Histamine is a histamine metabolite that is formed via acetyl-CoA-dependent N-acetylation of histamine by AANATL7 in D. melanogaster, polyamine N-acetyltransferase in F. hepatica, and the arylalkylamine N-acetyltransferases aaNAT2 and aaNAT5b in A. aegypti. It selectively inhibits sweet-almond β-glucosidase over yeast α-glucosidase in vitro (Kis = 0.035 and 20 mM, respectively). It also inhibits human glutaminyl cyclase (IC50 = 17 μM). N-acetyl Histamine has no effect on eosinophil activity and has been used as a negative control for histamine mediation of anaphylaxis. |
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