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GANT61
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
GANT61图片
CAS NO:500579-04-4
包装与价格:
包装价格(元)
10mg电议
25mg电议
50mg电议
100mg电议
10mM * 1mL in DMSO电议

产品名称
NSC136476, NSC-136476, GANT 61, GANT-61
产品介绍

生物活性

GANT61是GLI1和GLI2诱导的转录的抑制剂,以5μM的IC50抑制hedgehog,对其他途径(例如TNF和糖皮质激素受体基因反式激活)表现出选择性。

靶点信息

GLI1 (HEK293T cells expressing GLI1)
5 μM

化学数据

目录号A13252
作用机制Antagonist (拮抗剂)
M. Wt429.61
FormulaC27H35N5
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.500579-04-4
SynonymsNSC136476, NSC-136476, GANT 61, GANT-61
SMILESCN(C)C1=CC=CC=C1CN2CCCN(C2C3=CC=NC=C3)CC4=CC=CC=C4N(C)C

溶解度

In vitroDMSOInsoluble
WaterInsoluble
Ethanol11 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM23.28 mL116.38 mL232.77 mL
0.5 mM4.66 mL23.28 mL46.55 mL
1 mM2.33 mL11.64 mL23.28 mL
5 mM0.47 mL2.33 mL4.66 mL

*The above data is based on the productmolecular weight 429.61. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.