CAS NO: | 120373-36-6 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | Unoprostone, a prostaglandin F2α analogs (PGAs), activatesBK channelsto reduce oxidative stress- and light-induced retinal cell death, and phagocytotic dysfunction. Unoprostone reduces intraocular pressure and is used topically for glaucoma or ocular hypertension[1]. | ||||||||
体外研究 (In Vitro) | Pretreatment with Unoprostone (0.01, 0.1, 1 μM; 1 h before H2O2treatment) protects against H2O2-induced cell death in a concentration-dependent manner and the effect is significant at 0.1 μM and 1 μM concentrations[1]. Cell Viability Assay[1]
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体内研究 (In Vivo) | Unoprostone (0.06%, 0.12%; topical instillation; 3 μl) reduces mouse intraocular pressure (IOP) in a dose-dependent manner[3].
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Clinical Trial | |||||||||
分子量 | 382.53 | ||||||||
Formula | C22H38O5 | ||||||||
CAS 号 | 120373-36-6 | ||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |