CAS NO: | 55-06-1 |
包装 | 价格(元) |
100mg | 电议 |
500mg | 电议 |
1 g | 电议 |
5 g | 电议 |
生物活性 | Liothyronine sodium is an active form of thyroid hormone. Liothyronine sodium is a potent thyroid hormone receptorsTRαandTRβagonist withKis of 2.33 nM for hTRα and hTRβ, respectively[1][2][3]. | ||||||||||||||||
IC50& Target |
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体外研究 (In Vitro) | Liothyronine (T3, 100 nM) sodium stimulates the proliferation of hepatocarcinema cells in which TRβ1 is overexpressed[1]. Liothyronine sodium binds to human β1 thyroid hormone receptor (hTRβ1), and changes its conformation. Liothyronine sodium promotes growth, induces differentiation and regualtes metabolic effects[2]. | ||||||||||||||||
分子量 | 672.96 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C15H11I3NNaO4 | ||||||||||||||||
CAS 号 | 55-06-1 | ||||||||||||||||
中文名称 | 三碘代甲状腺素钠盐;碘塞罗宁钠 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) | ||||||||||||||||
溶解性数据 | In Vitro: 0.1 M NaOH : 12.5 mg/mL(18.57 mM;ultrasonic and adjust pH to 11 with NaOH) DMSO : 5.56 mg/mL(8.26 mM;ultrasonic and warming and heat to 60℃) H2O :< 0.1 mg/mL (ultrasonic;warming;heat to 60℃)(insoluble) 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo: 请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照In Vitro方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用;
以下溶剂前显示的百
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