CAS NO: | 1392809-08-3 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | MRL-871 (compound 3) is a potent and allostericretinoic acid receptor-related orphan receptor γt (RORγt)inverse agonists with anIC50of 12.7 nM. MRL-871 has a distinct isoxazole chemotype and effectively reducesIL-17amRNA production in EL4 cells[1]. |
体外研究 (In Vitro) | MRL-871 (compound 3; 10 μM, 24h) significantly reduces IL-17a mRNA expression 48-fold in EL4 cells[1]. |
分子量 | 444.79 |
Formula | C22H12ClF3N2O3 |
CAS 号 | 1392809-08-3 |
运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |