CAS NO: | 110368-33-7 |
包装 | 价格(元) |
10 mM * 1 mL in DMSO | 电议 |
5mg | 电议 |
10mg | 电议 |
50mg | 电议 |
100mg | 电议 |
200mg | 电议 |
500mg | 电议 |
生物活性 | Ch55 is a potent synthetic retinoid. Ch55 binds toRAR-αandRAR-β receptorswith high affinity. Ch55 displays low affinity for cellular retinoic acid binding protein (CRABP). Ch55 is a potent inducer of the differentiation of HL60 cells with an EC50of 200 nM. Ch55 can be used forcancerresearch[1][2]. | ||||||||||||||||
体外研究 (In Vitro) | Ch55 inhibits squamous cell differentiation of rabbit tracheal epithelial cells by inhibiting type I transglutaminase activity (EC50= 0.02 nM) and increasing cholesterol sulfate levels (EC50= 0.03 nM). Ch55 also induce differentiation of embryonic carcinoma F9 cells and melanoma S91 cells (EC50s = 0.26 and 0.5 nM, respectively), and inhibits the induction of ornithine decarboxylase activity in 3T6 fibroblasts (EC50= 1 nM)[1]. | ||||||||||||||||
分子量 | 364.48 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C24H28O3 | ||||||||||||||||
CAS 号 | 110368-33-7 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 |
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溶解性数据 | In Vitro: DMSO : 50 mg/mL(137.18 mM;Need ultrasonic) 配制储备液
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以下溶剂前显示的百
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