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Bovinic acid
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Bovinic acid图片
CAS NO:2540-56-9
包装与价格:
包装价格(元)
5mg电议
10mg电议

产品介绍

Bovinicacid是一种共轭亚油酸,具有抗癌和抗动脉硬化的活性。

Cas No.2540-56-9
别名共轭(9Z11E)亚油酸,Bovinic acid; 9Z,11E-CLA; Rumenic Acid
化学名9Z,11E-octadecadienoic acid
Canonical SMILESCCCCCC/C=C/C=C\CCCCCCCC(O)=O
分子式C18H32O2
分子量280.45
溶解度100mg/mL in DMSO & DMF
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Conjugated linoleic acid (CLA) refers to a family of eight geometric isomers of linoleic acid in which the two double bonds are contiguous. (The predominant form of linoleic acid in nature, 18:ω6, has double bonds at nine and 12, interrupted by a methylene carbon.) CLA is found in both meat and dairy products, but it is not found to any significant degree in plants. The predominant isomer of CLA in animal tissue is 9Z,11E; smaller amounts of 10E,12Z also occur. Various antioxidant and antitumor activities have been attributed to CLA or its downstream metabolites.[1] Reported health benefits of dietary supplementation with CLA have been attributed variously to competitive inhibition of Δ6-desaturase and/or PPARγ activation.[2]

Reference:
[1]. Shultz, T.D., Chew, B.P., Seaman, W.R., et al. Inhibitory effect of conjugated dienoic derivatives of linoleic acid and β-carotene on the in vitro growth of human cancer cells. Cancer Letters 63, 125-133 (1992).
[2]. Houseknecht, K.L., Vanden Heuvel, J.P., Moya-Camarena, S.Y., et al. Dietary conjugated linoleic acid normalizes impaired glucose tolerance in the Zucker diabetic fatty fa/fa rat. Biochemical and Biophysical Research Communications 244, 678-682 (1998).