CAS NO: | 1334526-14-5 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | (±)-ML 209 (compound 4n), a diphenylpropanamide, is a retinoic acid-related orphan receptorRORγantagonist with anIC50of 1.1 μM. (±)-ML 209 inhibits RORγt transcriptional activity with an IC50of 300 nM in HEK293t cells. (±)-ML 209 inhibits the transcriptional activity of RORγt, but notRORαin cells. (±)-ML 209 selectively inhibits murine Th17 cell differentiation without affecting the differentiation of naiveCD4+T cells into other lineages, including Th1 and regulatory T cells[1]. | |
IC50& Target[1] |
| |
分子量 | 441.52 | |
Formula | C25H31NO6 | |
CAS 号 | 1334526-14-5 | |
运输条件 | Room temperature in continental US; may vary elsewhere. | |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |