| CAS NO: | 65-71-4 |
| 包装: | 1g |
| 市场价: | 446元 |
Thymine是DNA的四个碱基之一，可以作为癌症治疗中5-氟尿嘧啶(5-FU)的靶标，其Km值为2.3μM。
| Cas No. | 65-71-4 |
| 别名 | 胸腺嘧啶 |
| Canonical SMILES | O=C1NC(C(C)=CN1)=O |
| 分子式 | C5H6N2O2 |
| 分子量 | 126.11 |
| 溶解度 | DMSO: 100 mg/mL (792.96 mM); Water: 5 mg/mL (39.65 mM) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a Km of 2.3 μM. [1]. Tuchman M, et al. Effects of uridine and thymidine on the degradation of 5-fluorouracil, uracil, and thymine by rat liver dihydropyrimidine dehydrogenase. Cancer Res. 1985 Nov;45(11 Pt 1):5553-6. |
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