您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > Thymine
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Thymine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Thymine图片
CAS NO:65-71-4
包装:1g
市场价:446元

产品介绍

Thymine是DNA的四个碱基之一,可以作为癌症治疗中5-氟尿嘧啶(5-FU)的靶标,其Km值为2.3μM。

Cas No.65-71-4
别名胸腺嘧啶
Canonical SMILESO=C1NC(C(C)=CN1)=O
分子式C5H6N2O2
分子量126.11
溶解度DMSO: 100 mg/mL (792.96 mM); Water: 5 mg/mL (39.65 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a Km of 2.3 μM.

[1]. Tuchman M, et al. Effects of uridine and thymidine on the degradation of 5-fluorouracil, uracil, and thymine by rat liver dihydropyrimidine dehydrogenase. Cancer Res. 1985 Nov;45(11 Pt 1):5553-6.