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25-Hydroxycholesterol-d6
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
25-Hydroxycholesterol-d6图片
CAS NO:88247-69-2
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品名称
25-羟基胆固醇 d6
产品介绍
25-Hydroxycholesterol-d6 是 25-Hydroxycholesterol 的氘代物。25-Hydroxycholesterol 是胆固醇的代谢产物,由巨噬细胞响应 Toll 样受体 (TLR) 激活而产生和分泌。25-Hydroxycholesterol 有效且选择性抑制 B 细胞产生 IgA,EC50约为 65 nM。
生物活性

25-Hydroxycholesterol-d6 is the deuterium labeled 25-Hydroxycholesterol. 25-Hydroxycholesterol is a metabolite ofcholesterolthat is produced and secreted by macrophages in response toToll-like receptor (TLR)activation. 25-hydroxycholesterol is a potent (EC50≈65 nM) and selective suppressor ofIgAproduction by B cells[1][2].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

分子量

408.69

Formula

C27H40D6O2

CAS 号

88247-69-2

中文名称

25-羟基胆固醇 d6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.