Irinotecan-d10 ((+)-Irinotecan-d10) hydrochloride is the deuterium labeled Irinotecan. Irinotecan ((+)-Irinotecan) is atopoisomeraseIinhibitor, preventing religation of the DNA strand by binding totopoisomeraseI-DNA complex^[1][2].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

633.20

C₃₃H₂₉D₁₀ClN₄O₆

718612-62-5

伊立替康 d10 (盐酸盐)

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.