CAS NO: | 2509447-07-6 |
包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
生物活性 | Amubarvimab (BRII-196) is a humanIgG1mAb that bind to non-competing epitopes on thereceptor binding domain (RBD)ofspike protein, with aKDof 5.88 nM. Amubarvimab can effectively neutralize SARS-CoV-2 variants[1][2]. |
体外研究 (In Vitro) | Amubarvimab shows specific activity against wild-type SARS-CoV-2 and no cross-reactivity against other coronaviruses[1]. |
体内研究 (In Vivo) | Amubarvimab (10-50 mg/kg; i.p.) in combination with romlusevimab significantly decreases viral load in the lungs, and reduces lung pathology in a Syrian golden hamster model of SARS-CoV-2 infection[1]. |
CAS 号 | 2509447-07-6 |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |