| CAS NO: | 879293-15-9 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
| 生物活性 | Ordesekimab (AMG 714; PRV-015) is a fully human IgG1κ anti-IL-15(Interleukin Related) monoclonal antibody. The binding of Ordesekimab toIL-15inhibits the interaction ofIL-15with the IL-2Rβ and common γ chain of theIL-15 receptorcomplex, but not with the IL-15Rα chain. Ordesekimab has the potential for study of nonresponsive celiac disease (NRCD)[1]. | |
| IC50& Target[1] |
| |
| 体外研究 (In Vitro) | The simultaneous binding of Ordesekimab (AMG 714) to the Fcγ receptor (R) IIIα expressed on natural killer (NK) cells and to the IL-15/IL-15Rα complex on cells such as monocytes may theoretically enable antibody-dependent cell-mediated cytotoxicity (ADCC) toward the IL-15Rα-expressing cells[1]. | |
| CAS 号 | 879293-15-9 | |
| 中文名称 | 奥司奇单抗 | |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
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