CAS NO: | 2573775-59-2 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | Cbl-b-IN-3 (Compound 23) is a casitas B-lineage lymphoma proto-oncogene-b (Cbl-b) inhibitor with anIC50of< 1 nM. Cbl-b is an E3 ubiquitin ligase that negatively regulates T-cell activation[1]. |
IC50& Target | IC50:< 1 nM (Cbl-b)[1] |
体外研究 (In Vitro) | Cbl-b-IN-3 (Compound 23) enhances IL-2 secretion by T-cells stimulated with an anti-CD3 antibody alone or in combination with an anti-CD28 antibody[1]. |
分子量 | 537.62 |
Formula | C30H34F3N5O |
CAS 号 | 2573775-59-2 |
运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |