CAS NO: | 2253937-12-9 |
包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
生物活性 | Acasunlimab (GEN1046) is a bispecific antibody (bsAb) targetingPD-L1and4-1BB. Acasunlimab enhances T-cell and NK-cell function through conditional4-1BBstimulation while constitutively blocking thePD-1/PD-L1inhibitory axis. Acasunlimab can be used in research ofcancer[1][2]. | ||||||||
体外研究 (In Vitro) | Acasunlimab (GEN1046; 0.001-1 μM; 0-525 min) 促进树突状细胞和 T 细胞之间的相互作用并增强 T 细胞活化[1]。 | ||||||||
体内研究 (In Vivo) | Acasunlimab (5 mg/kg; i.v.; 每周两次,共三个周期) 在双敲入 (dKI) 转基因 C57BL/6 小鼠中具有抗肿瘤活性并抑制肿瘤生长[1]。
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CAS 号 | 2253937-12-9 | ||||||||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |