| CAS NO: | 2158362-38-8 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
| 生物活性 | Neihulizumab (ALTB-168) is an immune checkpoint agonistic antibody that binds to humanCD162 (PSGL-1), leading to downregulation of activated T-cells. Neihulizumab can be uesd for steroid-refractory acute graft-versus-host-disease (SR-aGVHD), psoriasis, psoriatic arthritis and ulcerative colitis research[1]. |
| 体外研究 (In Vitro) | Neihulizumab 是一种针对 P-选择素糖蛋白配体-1 (PSGL-1) 的单克隆抗体。Neihulizumab 与人 PSGL-1 结合，从而优先诱导晚期活化 T 细胞的凋亡。在炎症部位，血管内皮表达 P-选择素，活化的 T 细胞与这些部位结合并通过 PSGL-1 的表达迁移。以这种方式，Neihulizumab 被认为靶向活化的 T 细胞并抑制运输到发炎组织部位[1]。 |
| CAS 号 | 2158362-38-8 |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
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