CI 972 anhydrous

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CI 972 anhydrous

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

115787-68-3

包装与价格：

产品介绍

CI 972 anhydrous 是一会有效的，具有口服活性的，竞争性的嘌呤核苷磷酸化酶(PNP)(K_i=0.83 μM) 抑制剂，正在开发作为 T 细胞选择性免疫抑制剂。

生物活性	CI 972 anhydrous is a potent, orally active, and competitive inhibitor ofpurine nucleoside phosphorylase (PNP)(K_i=0.83 μM) under development as a T cell-selective immunosuppressive agent^[1]^[2].
IC₅₀& Target	Ki: 0.83 μM (PNP)^[1]
体内研究 (In Vivo)	CI 972 anhydrous (5-150 mg/kg; p.o.) produces dose-dependent elevation of plasma inosine one hour after administration to rats^[1].
分子量	297.76
Formula	C₁₁H₁₂ClN₅OS
CAS 号	115787-68-3
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.