PD-1/PD-L1-IN-13 (Compound 43) 是一种有效的免疫检查点PD-1/PD-L1抑制剂,对 PD-1/PD- L1 相互作用的 IC50值为 10.2 nM。PD-1/PD-L1-IN-13 在 Hepa1-6 同系小鼠模型中促进 CD8+T 细胞活化并延缓肿瘤生长。
生物活性 | PD-1/PD-L1-IN-13 (Compound 43) is a potent immune checkpointPD-1/PD-L1inhibitor with anIC50value of 10.2 nM. PD-1/PD-L1-IN-13 promots CD8+T cell activation and delays the tumor growth in the Hepa1-6 syngeneic mouse model[1]. |
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |