Cetrorelix diacetate (SB-075 diacetate) is a potent gonadotropin-releasing hormone(GnRH)receptor antagonist with anIC₅₀of 1.21 nM^[1].

IC50: 1.21 nM GnRH^[1].

Cetrorelix diacetate inhibits growth of ES-2 cell line at 1000 ng/ml. Cetrorelix diacetate has comparable antiproliferative effects as GnRH-I agonists indicating that the dichotomy of GnRH-I agonists and antagonists might not apply to the GnRH-I system in cancer cells^[2].

1551.14

C₇₄H₁₀₀ClN₁₇O₁₈

130143-01-0

Ac-{2-Naph-Ala}-{Cl-Phe}-{3Py-Ala}-SY-{Cit}-LRPA-NH2

二醋酸西曲瑞克

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.