LH-RH (4-10) is a heptapeptide, one of major degradation products of luteinising-hormone releasing hormone (LHRH) via pituitary and hypothalamus. LH-RH (4-10) produced in macrophages and type II pneumocytes^[1].

The formation of LHRH 4-10, LHRH 7-10, and LHRH 6-10Co-incubation are inhibited by known enzyme inhibitors includingCaptopril(HY-B0368) (an ACE inhibitor),Thiorphan(HY-W013375) (an EP24.11 inhibitor), andEthylenediaminetetraacetic acid(HY-Y0682) (an EP24.15 inhibitor)^[1].
LH-RH (4-10) inhibits the binding of¹²⁵I-labeled GnRH to monoclonal antibody P₈16₆₂with an IC₅₀value of 23 pM^[2].

747.84

C₃₃H₅₃N₁₁O₉

51776-33-1

SYGLRPG-NH2

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.