DGN462 是一种有效的DNA烷基化剂,具有抗肿瘤活性,如抗急性髓系白血病 (AML)。DGN462 可以作为 ADC 毒素分子合成 ADC。
生物活性 | DGN462, a potentDNA-alkylatingagent, shows anti-tumor activity, such as acute myeloid leukemia (AML). DGN462 can be used as a cytotoxic component ofantibody-drug conjugates (ADCs)[1]. |
体外研究 (In Vitro) | DGN462 is a member of the DNA-alkylating indolinobenzodiazepine pseudodimers (IGNs) class[1].
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |